Celebrex Side effects

. What are side effects associated with Celebrex?

Of the Celebrex treated patients in controlled trials, approximately 4,250 were patients with OA, approximately 2,100 were patients with RA, and approximately 1,050 were patients with post-surgical pain. More than 8,500 patients have received a total daily dose of Celebrex of 200 mg (100 mg BID or 200 mg QD) or more, including more than 400 treated at 800 mg (400 mg BID). Approximately 3,900 patients have received Celebrex at these doses for 6 months or more; approximately 2,300 of these have received it for 1 year or more and 124 of these have received it for 2 years or more.

. In what populations is Celebrex contraindicated?

Celebrex™ is contraindicated in patients with known hypersensitivity to celecoxib.
Celebrex™ should not be given to patients who have demonstrated allergic-type reactions to sulfonamides.
Celebrex™ should not be given to patients who have experienced asthma, urticaria, or allergic-type NSAIDs have been reported in such patients.

. Should pregnant women take Celebrex?

There are no studies in pregnant women or nursing mothers. Therefore, Celebrex™ should not used during pregnancy or while nursing. In late pregnancy Celebrex may cause premature closure of the ductus arteriosus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Celebrex™ is not recommended in this population.

. Should individuals with hepatic impairment take Celebrex?

Celebrex™ capsules should be introduced at a reduced dose in patients with moderate hepatic impairment. Patients with severe hepatic impairment have not been studied, therefore, the use of Celebrex™ in these patients is not recommended at this time.